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Product Name MC-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C50H73N7O17 Molecular Weight 1044
463 Purity (HPLC) >= 95% Solubility DMSO
DBCO has been extensively used in copper-free click chemistry
specifically used in the strain-promoted azide-alkyne cycloaddition (SPAAC) reaction
Mal-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-Exatecan Size:25mg Product Name MC-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CASSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage
