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It is also a potent
Product Name DOTA-heptyne Synonyms CAS Number n/a Related CAS Molecular Formula C23H39N5O7 Molecular Weight 497
626 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCNC(=O)CCN2C(=O)C=CC2=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
which reacts with benzylguanine (BG)or chloropyrimidine (CP) derivatives
Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-Exatecan Size:25mg It is also a potentSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,
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