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DBCO-Propionyl-Val-Cit-PAB(m-PEG8) ligand It forms a covalent bond

SKU: 57803230875

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Description

It forms a covalent bond with the HaloTag protein

N-(dimethyl-d6)aniline Synonyms CAS Number n/a Related CAS Molecular Formula C9H12ClN Molecular Weight 175

01 SMILES CNC(=O)COC1=CC2=C(C=CC(=C2)N(C)C2=NC(=NC=C2Cl)N2C[C@@H](C)C[C@@H](C)C2)N(C)C1=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

NCCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Propionyl-Val-Cit-PAB(m-PEG8) ligand It forms a covalent bondSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through selection

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