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enabling efficient and selective conjugation of the payload to the linker
132–139 (2013)
Datasheet MSDS
1039/d3md00569k
DBCO-Hexanoyl-Val-Cit-PAB(m-PEG8)-PNP Size:100mg enabling efficient and selective conjugationSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine
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