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Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg Signal Transduction and Targeted Therapy

SKU: 94042944352

4.7
USD495.00 USD516.00

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Description

Signal Transduction and Targeted Therapy

519 Purity (HPLC) >= 95% Solubility DMSO

Product Name Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C43H71N7O15 Molecular Weight 926

Development of PDE6D and CK1a Degraders through Chemical Derivatization of FPFT-2216

Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg Signal Transduction and Targeted TherapySOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further

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