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Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan deuterium-labeled-ketone CA-SulfoCy5 is a HaloTag ligand

SKU: 96130969989

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Description

CA-SulfoCy5 is a HaloTag ligand with SulfoCyanine5 dye

Product Name MC-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C45H62N8O16 Molecular Weight 971

Product Name Thalidomide-O-PEG1-C2-Br Synonyms Thalidomide-4'-O-PEG1-C2-Br CAS Number n/a Related CAS Molecular Formula C17H17BrN2O6 Molecular Weight 425

the labeling efficiency of tetramethylrhodamine maleimides and iodoacetamides is often lower compared to that of other tetramethylrhodamine labeling dyes

Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan deuterium-labeled-ketone CA-SulfoCy5 is a HaloTag ligandSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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