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When the probe binds to its cellular targets
NBD-TM proved to be the most rapid scavenger of HOCl when compared with boronate- and aminophenyl-based fluorogenic probes in a study for monitoring the chlorinating activity of Myeloperoxidase (MPO)
SNAP-tag reacts with covalently with benzylguanine (BG)or chloropyrimidine (CP) derivatives
Product Name: 5-ROX Synonyms: 5-Carboxy-X-rhodamine CAS Number: N/A Molecular Formula: C33H30N2O5 Molecular Weight: 534
Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan texas red When the probe binds toSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by
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