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Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8) Size:100mg ROX is a red-emitting rhodamine

SKU: 9724223920

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Description

ROX is a red-emitting rhodamine dye possessing high brightness and fluorescence quantum yield

003 Purity (HPLC) >= 95% Solubility DMSO

CP-Cy5 is a SNAP-tag substrate with Cyanine5 dye

Development of PDE6D and CK1a Degraders through Chemical Derivatization of FPFT-2216

Mal-Propionyl-PEG2-Val-Cit-PAB(m-PEG8) Size:100mg ROX is a red-emitting rhodamineSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX

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